Saxagliptin hydrate

Iupac Name：(1S,3S,5S)-2-[(2S)-2-amino-2-(3-hydroxy-1-adamantyl)acetyl]-2-azabicyclo[3.1.0]hexane-3-carbonitrile;hydrate

CAS No.: 945667-22-1

Molecular Weight：333.432

Introduction:

Saxagliptin hydrate, with the chemical formula C18H25N3O2S·xH2O and CAS registry number 945667-22-1, is a compound used in the treatment of type 2 diabetes mellitus. It is an inhibitor of dipeptidyl peptidase-4 (DPP-4), an enzyme involved in the degradation of incretin hormones. By inhibiting DPP-4, Saxagliptin hydrate increases the levels of active incretin hormones, which in turn stimulates insulin secretion and reduces glucagon levels. This compound is typically administered orally and has shown efficacy in improving glycemic control in patients with type 2 diabetes. Saxagliptin hydrate is generally well-tolerated, with common side effects including upper respiratory tract infections, headache, and nasopharyngitis. It is important to note that the information provided here is a summary and should not replace professional medical advice. Please consult a healthcare provider for more information on the use of Saxagliptin hydrate.