Medroxyprogesterone Acetate

Iupac Name：[(6S,8R,9S,10R,13S,14S,17R)-17-acetyl-6,10,13-trimethyl-3-oxo-2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthren-17-yl] acetate

CAS No.: 71-58-9

Molecular Weight：386.53

With WC, DMF

Introduction: MPA, 17-acetyloxy-6α-methylpregn-4-ene-3,20-dione (Provera), adds a6α-methyl group to the basic 17α-hydroxyprogesteronestructure to greatly decrease the rate of reduction of the 4-ene-3-one system. The 17α-acetate group also decreases reductionof the 20-one, similar to the 17α-caproate. MPA isvery active orally and has such a long durationof action intramuscularly that it cannot be routinely usedintramuscularly for treating many menstrual disorders.